Topical Finasteride, Is It as Effective as Oral Finasteride?
Topical Finasteride, Is It as Effective as Oral Finasteride?
Finasteride has long been a go-to treatment for male pattern baldness, with the oral version (commonly known as Propecia) widely prescribed to slow hair loss and stimulate regrowth. But what about topical finasteride? In recent years, it’s gained attention as a potential alternative with fewer side effects. So, the question is: is topical finasteride as effective as oral finasteride?
Let’s take a closer look.
The Basics: Oral vs. Topical Finasteride?
Oral finasteride works by inhibiting the enzyme 5-alpha reductase, which converts testosterone into dihydrotestosterone (DHT)—a hormone responsible for shrinking hair follicles. By lowering DHT levels, hair loss can be slowed or even reversed.
Topical finasteride aims to do the same thing, but with a twist: it’s applied directly to the scalp. The idea is to reduce DHT levels locally (on the scalp) while minimizing systemic absorption into the bloodstream—thus reducing the risk of side effects.
What Does the Research Say?
Several recent studies have compared topical and oral finasteride, and the results are promising.
Effectiveness: Clinical trials suggest that topical finasteride can be nearly as effective as oral finasteride in reducing hair loss and increasing hair count. One notable study published in the Journal of the American Academy of Dermatology (2021) found that both formulations significantly improved hair density, with the topical version showing comparable results to oral finasteride over 24 weeks.
Side Effects: A key benefit of topical finasteride appears to be fewer systemic side effects. While oral finasteride can cause issues like decreased libido, erectile dysfunction, or mood changes in a small percentage of users, these are reportedly less common with topical application—likely due to reduced absorption into the bloodstream.
Who Might Prefer Topical Finasteride?
Topical finasteride could be a great option for men who are sensitive to side effects from the oral version, those starting hair loss treatment who want a gentler introduction or patients combining treatments, such as using topical minoxidil alongside finasteride.
However, every person is different. Some people may find topical application inconvenient or may not respond as well to it, it is always important to discuss all your options with your Trichologist.
The Bottom Line
Topical finasteride is emerging as a strong contender to oral finasteride, offering similar results with potentially fewer side effects. While more long-term studies are needed, current evidence supports its use as an effective treatment for androgenetic alopecia.
If you’re considering finasteride—oral or topical— contact us today! Our experienced Trichologist can help you weigh the pros and cons based on your medical history, hair loss pattern, and lifestyle.